How & we know if talc is causative agent if early stage ovarian cancer can’t be detected?

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How & we know if talc is causative agent if early stage ovarian cancer can’t be detected?

Brief review of Johnson and Johnson lawsuits

Use Meta-analysis jounals to gather literature and evidence find the connection between talcum powder and ovarian cancer and other associated cancers use examples of randomised experirnents risk factors associated with talcum powder, the time scales, thus progression of the cancer over life time use?

Connection between absestos talcum *banned* and absestos free taclum? Lack of in vitro studies which test whether talc causes cancer g. tissue culture using ovarian cell lines and adding talc powder to see whether cells become cancerous.

useful info:

. Jacky Fox claimed that she used talc powder for many years. She was born in 1953 and died in 2015 when she was 62 years old.

Positive notion that asbestos is linked with ovarian cancer

. Asbestos containing talc was banned in 1970s. There is a possible link that she was using asbestos containing talc powder while being young and therefore eventually got cancer later in her life due to asbestos.

Can we trust the word of Johnson & Johnson?

.J&J had similar case with formaldehyde which is known carcinogen. J&J had to remove formaldehyde from baby shampoo due to California safety regulations, consumers’ and activists’ pressure.

‘Under the Federal Food, Drug and Cosmetic act (FD&C Pd), cosmetic products and ingredients, with the exception of colour additives, do not have to undergo FDA review or approval before they go on the market.

Questions:

‘Most ovarian cancers are detected at late stage and have poor prognoses. How & we know if talc is causative agent if early stage ovarian cancer can’t be detected? ‘Promotes progression at late stage?