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Instructions: The Whitehall study is a ground-breaking longitudinal (prospective cohort) study that clearly demonstrated the association between social determinants of health (the social gradient) and morbidity and mortality (cardiovascular disease) in a population of British civil servants (Breeze et al., 2001; Chandola et al., 2008; Marmot et al., 1978). In no more than 1,000 words please address the following short-answer questions: What is the sampling frame for each phase of the Whitehall study (Whitehall I and II)? How was disease risk assessed (both in data collection and analysis) in each of the three studies, and why? To what extent can the results of each of the three studies can be generalised to other populations (include reasons for your answer)? Would it be feasible to conduct a similar study in Australia using an existing cohort such as the 45 and up study cohort, or the Australian Women’s longitudinal study cohort? Why or why not? Complete and submit the assignment by the end of Module 2. Assessment criteria Knowledge and understanding of prospective cohort studies Knowledge and understanding of social determinants of health Knowledge an understanding of the concepts of sampling and bias Use of mathematical concepts to describe sampling frame and disease risk Interpretation of the findings of the Whitehall study and its generalisability to other populations Academic presentation including accurate referencing using APA style